Browse Technologies

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TagDock: An Efficient Rigid Body Molecular Docking Algorithm For Three Dimensional Models of Oligomeric Biomolecular Complexes With Limited Experimental Restraint Data

TagDock is an efficient rigid body molecular docking algorithm that generates three-dimensional models of oligomeric biomolecular complexes in instances where there is limited experimental restraint data to guide the docking calculations. Through "distance difference analysis" TagDock additionally recommends followup experiments to further discriminate divergent (score-degenerate) clusters of TagDock's initial solution models


Licensing Contact

Masood Machingal

615.343.3548

An Imaging Approach to Detect Parathyroid Gland Health During Endocrine Surgery

Vanderbilt researchers have designed a laser speckle imaging device to detect parathyroid gland viability during endocrine surgery, during which otherwise healthy parathyroid glands are prone to devascularization leading to long-term hypocalcemia. Currently, the surgeon must use his or her best judgement regarding the health of the parathyroid gland. This technology removes the guess work from the decision and provides a real-time assessment of the parathyroid viability.


Licensing Contact

Masood Machingal

615.343.3548
Medical Devices

Optical tweezers for nanoscale-biological materials

Optical tweezers have been used to study microscopic biological materials, but their application on the nanoscale has thus far been limited by technical constraints. To enable their use on the nanoscale, researchers at Vanderbilt have developed an optical trapping platform for targeting these nanoscale materials without destroying the sample.


Licensing Contact

Philip Swaney

615.322.1067

Wireless soft robots for in vivo mucus property measurement

The material properties of mucus, such as viscosity and pH, provide information about the well-being of various organ systems. To improve accessibility to mucus sites from throughout the body and increase the validity of measurements, Vanderbilt researchers have developed a wireless millimeter-scale soft robot for direct and accurate mucus sensing throughout the body.


Licensing Contact

Philip Swaney

615.322.1067
Medical Devices

Novel Growth Factor for Liver Regeneration

Liver transplantation is the only cure for end-stage liver disease, but donor organ scarcity limits access for millions. Split liver transplantation could help bridge this gap, but the regeneration of partial organs is critical to broadlyimplementing this approach. Vanderbilt University researchers have identified a growth factor that promotes liver growth that could be used to improve patient outcomes and increase accessibility to liver transplantation.


Licensing Contact

Cameron Sargent

615.322.5907
Surgery
Protein/Peptide
Protein/Peptide

Silicone Airway Stent with Wirelessly Actuated Cilia for Mucus Removal

Various widespread diseases associated with airway constriction can be combatted using airway stents. However, such stents are either prone to clogging themselves or tend to invade neighboring tissue. Vanderbilt engineers have developed a technology that avoids both of these pitfalls by combining the use of tissue-friendly silicone with active cilia for mucus clearing.


Licensing Contact

Philip Swaney

615.322.1067
Medical Devices

Quantitative rapid diagnostic platform using porous silicon on paper

This technology combines the sensitivity of porous silicon with the speed of lateral flowassays to create a point-of-care diagnostic platform capable of rapidly and accuratelymeasuring biomarkers.


Licensing Contact

Cameron Sargent

615.322.5907
Diagnostics
Infectious Disease

Zero-waste, pre-portioned sunscreen capsule

Vanderbilt has developed an innovative sunscreen delivery system that promotes the proper usage of sunscreen while also using zero-waste packaging.


Licensing Contact

Carlos Detres Roman

615.343.2430

Anti-inflammatory microparticles for sustained ocular drug delivery

Vanderbilt researchers have developed an injectable drug delivery vehicle using microparticles (MPs) that not only provide sustained cargo delivery over extended time but also play a therapeutic role themselves in reducing inflammation. This drug delivery platform can be used in treating ocular diseases such as glaucoma and traumatic optic neuropathy, as well as other inflammatory diseases throughout the body like peripheral arterial disease and osteoarthritis.


Licensing Contact

Taylor Jordan

615.936.7505

ML-powered software for planning sleep apnea surgery

High-resolution pharyngeal manometry (HRM) provides an inexpensive and objective method for analyzing the pharynx during natural sleep and can be utilized to select candidates for certain surgical procedures for obstructive sleep apnea (OSA).


Licensing Contact

Chris Harris

615.343.4433