Browse Technologies

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Engineering the Sodium/Iodide Symporter for Enhanced Targeted Internal Radiotherapy

The Sodium/Iodide symporter (NIS) is a critical protein that facilitates the active transport of iodide into thyroid cells, essential for synthesizing thyroid hormones. Recent advancements in engineering NIS variants aim to selectively transport oxyanions, offering innovative therapeutic strategies for cancer treatment in the thyroid and elsewhere while minimizing side effects.


Licensing Contact

Carlos Detres Roman

615.343.2430
Therapeutics
Genomic Therapy

EndoPBR: Photorealistic Endoscopic Surgery Simulation

EndoPBR generates photorealistic surgical simulation data using advanced neural rendering and physically-based lighting models.


Licensing Contact

Philip Swaney

615.322.1067
Opthamology
Small Molecule

Novel Curcumin Derivatives with Enhanced Anti-Inflammatory Properties

Vanderbilt researchershave identified two novel curcumin derivative compounds withenhanced anti-inflammatory activity and improvedtherapeutic potential.


Licensing Contact

Carlos Detres Roman

615.343.2430

Genetic engineering approach for enhancing recombinant protein production by mammalian cells

Vanderbilt researchers have developed a novel approach to enhance recombinant protein production in mammalian cell culture systems by overexpressing specific metabolic proteins in these cells to achieve higher monoclonal antibody titers and increased cell-specific productivity compared to conventional expression systems.


Licensing Contact

Cameron Sargent

615.322.5907

AI-Driven Molecular Skin Analysis & Personalized Skincare

Vanderbilt researchers have developed a novel skin assessment platform that analyzes the molecular composition of skin using artificial intelligence to match individuals with optimal skincare products.


Licensing Contact

Philip Swaney

615.322.1067

Oxygen-Tolerant Probiotic Therapy for Intestinal Inflammatory Diseases

Vanderbilt researchers have engineered Bacteroides thetaiotaomicron, an obligate anaerobe, to endure oxygen-rich conditions in the gut, enhancing the survival and functionality of these probiotics used to treat inflammation.


Licensing Contact

Cameron Sargent

615.322.5907

Method and System for Automating Oxygen Monitoring and Dosing in Real Time for Patient on Oxygen Therapy

Vanderbilt researcher, Lisa Lancaster, MD, has developed a novel device to monitor the flow as well as adjust actively the levels of oxygen that pass to a patient suffering from Idiopathic Pulmonary Fibrosis or other causes of hypoxic lung disease. Standing out of the pack, this device ensures that patients exerting themselves are given enough oxygen while actively reducing the dosage, to prevent further damage, when the same patient is resting.


Licensing Contact

Masood Machingal

615.343.3548

Inventors

Lisa Lancaster
Medical Devices
Pulmonary/Respiratory

Cutting-Edge Brain Age Estimation from Diffusion MRI

Vanderbilt researchers have developed a novel brain age estimation framework that leverages diffusion MRI to capture microstructural changes associated with aging. This innovative approach outperforms conventional T1-weighted MRI methods by focusing specifically on subtle brain changes, providing a powerful tool for early detection of neurodegenerative diseases and enabling earlier clinical intervention.


Licensing Contact

Virinchi Juttukonda

615.343.2430

Surface Active Ionic Liquid with Activity in Aqueous and Non-aqueous Media

Surface active ionic liquids (SAILs) exhibit extraordinary properties both as solvents and superior surfactants. However, existing SAILs have limitations that prevent their full potential from being realized. To address this, researchers at Vanderbilt have synthesized a promising chiral SAIL that can be used as a detergent or stabilizing agent at all kinds of interfaces and is made from an inexpensive and biodegradable starting material.


Licensing Contact

Carlos Detres Roman

615.343.2430

Dual Interlocked Logic (DIL) Circuit

Vanderbilt researchers have developed a novel combinatorial logic circuit that prevents the propagation of signal glitches such as those caused by radiation-induced transients. The interlocked-feedback circuit accomplishes this without the loss of any speed. The circuit is designed for robustness in both combinatorial and sequential logic applications.


Licensing Contact

Virinchi Juttukonda

615.343.2430