Browse Technologies

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Lickometer: Instrument for measuring rodent drinking behavior

Researchers at Vanderbilt University designed an instrument capable of higher accuracy and analyzing lick microstructure compared to current available models. This device is compatible with classic ventilated home cages, making it easy to build and use with an intuitive touchscreen graphical user interface. The system tracks two-bottle choice licking behavior in up to 18 rodent cages, or 36 single bottles, on a minute-to-minute timescale controlled by a single Arduino microcontroller. Ultimately, the system measures drinking preference over time and changes in bout microstructure, with undisturbed recordings lasting up to 7 days.


Licensing Contact

Greg Pawel

615.343.0996

Use of Fluid Shear Stress Treatment to Enhance T Cell Activation

Researchers at Vanderbilt University have developed a technique to enhance immune cell activation by exposing cells to mechanical force while culturing. Proof-of-concept data indicate that activating immune cells with this method may improve therapeutic efficacy and reduce manufacturing expenses, making powerful CAR T cell therapies more accessible to patients in need.


Licensing Contact

Cameron Sargent

615.322.5907

Improved Biomanufacturing Using Biological Clock Control for High Yield/Low Cost Bioproduct

A team of researchers at Vanderbilt University has developed a method of manipulating the circadian clock of cyanobacteria. This biological manipulation is used to increase gene expression in target genes that produce biofuel and high-value bioproducts, such as pharmaceuticals and cosmetics from precursor-expressing genes. Altering the circadian rhythm in the bacteria provides an improved approach to bioproduct development on a large scale using sunlight as a zero--cost energy solution.


Licensing Contact

Masood Machingal

615.343.3548

Anti-human Myeloid Cell Nuclear Differentiation Monoclonal Antibody

The antibody is a rat IgG1 monoclonal, clone 3C1.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Antibody
Assays/Screening

Purified Bovine cAMP and cGMP Dependant Protein Kinases

This research targets PKA, PKG.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Jackie Corbin
Research Tools
Cardiovascular
Protein/Peptide

Scn1a Knockout Mouse Genetic Model of Epilepsy

This is a unique genetically modified strain ofmice that models Dravet syndrome, a severe infant-onset epileptic encephalopathy. They are maintained on apure 129S6/SvEvTac genetic background to facilitate genetic studies.


Licensing Contact

Karen Rufus

615.322.4295
Research Tools
Animal Model

Immortalized Mouse Epididymal Epithelial Cell Lines

These cell lines are useful for studying the regulation of tissue-specific gene expression, and may also be used to identify epididymal-specific transcription factors involved in expression of specific proteins in the epididymis.


Licensing Contact

Cameron Sargent

615.343.2430
Research Tools
Genitourinary
Cell Line

GluN2B Floxed Mice (also called NR2B, glutamate receptor 2B)

Allows for targeted deletion of the GluN2B subunit of NMDA receptors in specific cells or at specific times during development, juvenile, or adult stages. C57BL6/J background


Licensing Contact

Cameron Sargent

615.343.2430

Inventors

Eric Delpire
Research Tools
Neuroscience/Neurology
Animal Model

Endothieal Nitric Oxide Synthase Null Mice (db/db background)

This research targets eNOS.


Licensing Contact

Karen Rufus

615.322.4295

Inventors

Raymond Harris
Research Tools
Cardiovascular
Animal Model

Rabbit-Anti-mouse Pancreatic and Duodenal Homebox Gene-1 Antibody

This research targets Pdx-1.


Licensing Contact

Cameron Sargent

615.343.2430

Inventors

Christopher Wright