This initiative aims to transform the hospital waiting room experience by providing patients with a curated playlist of stories, offering comfort and connection during a typically isolating and stressful time. The project will develop a user-friendly digital platform to deliver these stories and potentially allow patients to contribute their own, with plans for wider implementation across hospitals.
The team is developing the Intrinsic Glove, a semi-rigid, flexible orthosis designed to improve hand trauma management by promoting safe positioning, early motion, and compression. This innovative glove enhances patient care and provider efficiency by enabling quick, effective positioning and reducing setup time significantly.
This proposal aims to develop poly(thioketal thiourethane) (PTKTUR) elastomers for surgical mesh that supports tissue regeneration and degrades in response to cell-secreted reactive oxygen species, with tunable mechanical properties matching patient biology.
This technology will use the bacterial hydrophilin DtpA to enhance the stability and viability of probiotics and enzymes under extreme conditions, improving strain diversity, bacterial recovery, and enzyme protection for microbiome-based therapeutics.
SANDI supports neurodiverse individuals, particularly those on the autism spectrum, in achieving driving independence by addressing barriers like anxiety and sensory overload through structured, repetitive learning. This innovative simulator enhances confidence, provides greater accessibility to driving skills, and promotes long-term social and economic inclusion.
This project seeks to develop scalable, 1,000-channel CAPCAS microbioreactor systems to accelerate AI/ML-driven advancements in cell-culture control for biologically produced pharmaceuticals and industrial chemicals. The outcome will enable more efficient cell-line identification, media optimization, and bioreactor control, ultimately transforming the BioPharma industry by improving automation and scaling of cell-culture studies.
The team is developing Tamm polariton multi-frequency thermal emitters and filters for enhanced gas sensing, with applications in semiconductor monitoring and healthcare, such as breath analysis for early disease detection, based on AI-driven design from the Caldwell Lab at Vanderbilt.
The team is developing Peabody Research Concierge (PRC), a conversational AI designed to enhance the matching process between Vanderbilt faculty and relevant research funding opportunities, optimizing resource discovery through AI-driven insights based on individual expertise.
The team will create a patient-centered, AI-powered chatbot to explain APOL1 genetic test results, guide kidney health behaviors, and reduce anxiety, addressing the national shortage of genetic counselors and improving the communication of genetic test results for kidney disease risk.
The team aims to develop a novel oxygen regulator with an auto-titration algorithm that uses SpO2 and activity data from wearables to automatically adjust oxygen flow rates, improving dosing accuracy and patient health outcomes. This closed-loop system offers personalized oxygen therapy, eliminating the need for manual adjustments and ensuring continuous, optimal oxygen levels.
The team aims to create a portable extracorporeal life support system that integrates a blood pump, oxygenator, and user interface, enabling ambulatory ECMO use to improve patient mobilization and outcomes, particularly for those awaiting lung transplants.
The team will develop a platform using phage display libraries to identify antibody variants specific to targeted tissues, enhancing the development of biologics for immune-oncology, autoimmunity, and other diseases through in vivo screening and next-generation sequencing.
The Courageous Voices in Action (CVA) seeks to develop a scalable curriculum focused on moral courage, leadership, and cultural-religious literacy that produces knowledgeable leaders who can challenge injustice and support LGBTQIA+ thriving.
The team is advancing a portable Dynamic Organ Storage System (DOSS) for organ transports. This system maintains and monitors a uniform organ temperature and ensures a steady supply of essential energy substrates, thus preventing cellular damage and temperature gradients.
Image Assist is a unique clinical photography tool that uses dynamic digital frames to take patient pictures accurately as per ASPS/PSF clinical photography guidelines and subtract noise. This technology was inspired by the concept of mobile check deposit.
The team aims to develop a molecule that inhibits bacterial movement during UTI infection, thus preventing bacteria from escaping antibiotics and forming recurrent infections. This strategy could significantly reduce recurrent, resistant infections, particularly in UTIs.
An innovative skin intelligence platform that uses skin mass spectrometry (MS) data to analyze the detailed molecular makeup of an individual’s skin and make skin product recommendations accordingly.
The TissueAb team seeks to enhance the technology that employs phage display libraries to identify tissues or cell type-specific antibodies (Ab) for targeted therapies. This technology will broadly apply to immune-oncology, autoimmunity, rare, and infectious diseases.
The team seeks to address the societal imperative of literacy by developing a technology that will facilitate dialogue reading between caregivers and young children. These interventions involve encouraging children to engage in conversations around books, rather than just passively listening.
SENSE Theatre is a unique intervention research program for youth, 10-16 years of age, with autism spectrum disorder (ASD). It is a performance-based intervention targeting social skills that includes trained peer actors and theatretechniques
The iTELL framework restructures text-based learning materials into individual web apps where students can read text content, participate in interactive exercises, and watch educational videos.
The project aims to further develop a technology around optimizing the routing and charging of mixed-fleet transportation and last-mile freight resources (e.g., buses and trucks).
DAGCAP aims to create a streamlined and automated curation system that mitigates challenges associated with medical charting. Increases in the quality of curation would drastically expand research, clinical, and operational capabilities across oncology care and research.
GownCard is an internally-developed, app-based surgical team information management system used by nurses, scrub techs, and surgeons to eliminate perioperative inefficiencies.
This injectable gelatin-based hydrogel promotes the growth of large blood vessels in a spatially controlled manner to restore blood flow to inadequately supplied areas. Because this hydrogel is formulated without encapsulated growth factors or cells, it can be easily translated to clinical applications.
The project aims to develop a system to support patient execution of DIBH. The system will feed, real-time, to software driving a VR display to provide visual feedback to patients on their DIBH.