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Discovery points to new cancer immunotherapy option

An international team involving Vanderbilt researchers has discovered that a new “checkpoint” protein on immune system cells is active in tumors, and that blocking it — in combination with other treatments — is a successful therapeutic approach in mouse models of cancer.


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Amy and Barry Baker Lab cancer immunotherapy Cancer Research checkpoint inhibitors department of otolaryngology Flow Cytometry Shared Resource immune system immunotherapy t cell Vanderbilt Ingram Cancer Center Vanderbilt Institute for Infection Immunology and Inflammation Young Kim

Team’s findings show glutamine metabolism affects T cell signaling

Team’s findings show glutamine metabolism affects T cell signaling


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Autoimmune disease cancer immunotherapy CAR T Therapy Cell Cell Metabolism center for immunobiology glutamine immunotherapy inflammation jeffrey rathmell NCI NHLBI NIH. Pathology microbiology and immunology t cell
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