Thin Films & Nanomaterials

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Optical tweezers have been used to study microscopic biological materials, but their application on the nanoscale has thus far been limited by technical constraints. To enable their use on the nanoscale, researchers at Vanderbilt have developed an optical trapping platform for targeting these nanoscale materials without destroying the sample.

Vanderbilt inventors have developed a one-step hydrosilylation synthesis of azide surfaces for the preparation of click chemistry compatible substrates. In this process, an organic azide is formed in a single step on a hydrogen-terminated silicon support, yielding a surface that is ready to undergo click reactions as desired. Simple, efficient, and versatile, click chemistry is widely used and is particularly useful for biosensing applications. A click reaction can be utilized to attach a molecular or biological probe for point-of-care diagnostics and chemical screening.

Vanderbilt researchers have developed a new system for transporting and sorting nanoscale and mesoscale particles and biomolecules. The system is able to achieve size-based sorting and captures/arranges the particles within a few seconds, which is significantly faster than the existing method of diffusion-based transport.