Infectious Disease

Displaying 1 - 7 of 7


Genetically Modified Cell Line for Enhanced Viral Vector Manufacturing

Recent FDA approvals have spurred the demand for viral vector products,prompting the need for more efficient bioproduction methods. In this context,Vanderbilt researchers have engineered a new cell line with significantlyenhanced viral production capabilities compared to traditional cell lines. Thisinnovation is expected to lead to substantial cost savings in viral vectorproduction and improved viral products, two key advantages in the industry.


Licensing Contact

Cameron Sargent

615.322.5907

Genetic engineering approach for enhancing recombinant protein production by mammalian cells

Vanderbilt researchers have developed a novel approach to enhance recombinant protein production in mammalian cell culture systems by overexpressing specific metabolic proteins in these cells to achieve higher monoclonal antibody titers and increased cell-specific productivity compared to conventional expression systems.


Licensing Contact

Cameron Sargent

615.322.5907

New antibiotics against new targets in multi-drug resistant microorganisms

New everninomicin antibiotics including a potent bifunctional antibiotic natural product targeting two different and distant ribosomal sites are under development and can be readily produced using synthetic biology. Developing resistance to this bidentate antibiotic should be very difficult for pathogenic microorganisms.


Licensing Contact

Mike Villalobos

615.322.6751
Therapeutics
Infectious Disease
Small Molecule

Quantitative rapid diagnostic platform using porous silicon on paper

This technology combines the sensitivity of porous silicon with the speed of lateral flowassays to create a point-of-care diagnostic platform capable of rapidly and accuratelymeasuring biomarkers.


Licensing Contact

Cameron Sargent

615.322.5907
Diagnostics
Infectious Disease

Targeted photodynamic therapy for S. aureus infections

Vanderbilt researchers have developed a combination photodynamic therapy (PDT) for targeting MRSA infections in skin that is not only effective but also HIGHLY SPECIFIC and LESS SUSCEPTIBLE TO RESISTANCE, adding a much needed therapy to our quickly depleting arsenal against this pathogen.


Licensing Contact

Cameron Sargent

615.322.5907

Wolbachia genetic tools for population control of harmful insects

Vanderbilt scientists have engineered transgenic methods for controlling the populations of insects, including infectious disease vectors like mosquitoes and agricultural pests that destroy crops and livestock.


Licensing Contact

Cameron Sargent

615.322.5907

Targeted light-based therapy for acne

Vanderbilt researchers have developed a photodynamic therapy (PDT) for effectively and specifically treating acne, the most common skin condition.


Licensing Contact

Cameron Sargent

615.322.5907
Therapeutics
Small Molecule