Now in a study published in the journal PLOS ONE, Vsevolod Gurevich, PhD, and colleagues show that a glycine residue at the beginning of the finger loop is critical for the arrestin-GPCR interaction.
Cellular signaling pathways involved in everything from the proliferation of fatty tissue to the death of neurons in the brain are tightly regulated by “cascades” of sequentially activated enzymes, MAP kinases.
