Medical Imaging

Displaying 1 - 10 of 35

Cutting-Edge Brain Age Estimation from Diffusion MRI

Vanderbilt researchers have developed a novel brain age estimation framework that leverages diffusion MRI to capture microstructural changes associated with aging. This innovative approach outperforms conventional T1-weighted MRI methods by focusing specifically on subtle brain changes, providing a powerful tool for early detection of neurodegenerative diseases and enabling earlier clinical intervention.

Licensing Contact

Virinchi Juttukonda

615.343.2430

Inventors

Chenyu Gao, Bennett Landman, Michael Kim
Category:
Diagnostics Medical Imaging

MRI COIL ARRAY ENABLING FOCUSED ULTRASOUND OUTSIDE THE MRI ENVIRONMENT

This technology pairs a novel coil design with patient-specific stereotactic frames for precise delivery of focused ultrasound (FUS) during neuromodulation therapies. This innovative methodology enables patients to receive therapy while outside the MR environment and significantly increases the precision of noninvasive neuromodulation techniques, making treatments more accessible and effective.

Licensing Contact

Chris Harris

615.343.4433

Inventors

Charles Caskey, Limin Chen, William Grissom, Peter Konrad, Benoit Dawant, William Rodriguez, Xinqiang Yan, Thomas Manuel, Marshal Phipps, Jiro Kusunose, John Grimes
Category:
Medical Devices Medical Imaging

Bioresorbable RF Coils for Post-Surgical Monitoring by MRI

Vanderbilt researchers have developed bioresorbable RF coils to improve the signal-to-noise ratio (SNR) for use in post-surgical monitoring.

Licensing Contact

Chris Harris

615.343.4433

Inventors

Mark Does, John Rogers
Category:
Diagnostics Medical Imaging

PIQASO: A rigid phantom for comprehensive end-to-end evaluation of online adaptive radiotherapy systems

There is currently no radiotherapy phantom capable of quantitatively assessing all components of an online adaptive radiotherapy (online ART) system in a comprehensive end-to-end test.Represented here is a novel, rigid phantom that can simultaneously evaluate an online ART system's image acquisition, deformable image registration, contour propagation, plan re-optimization, dose calculation, and beam delivery in a single process that is robust, quantitative, and convenient.

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Adam Yock, Abby Dare, Michael Price
Category:
Diagnostics Medical Devices Medical Imaging

Heterogeneous catalysis of NMR Signal Amplification by Reversible Exchange(SABRE)

Vanderbilt researchers have developed heterogeneous catalysis and catalyst for the NMR Signal Amplification by Reversible Exchange (SABRE) hyperpolarization process. Coupled with the researchers' development of a method to perform SABRE in aqueous solutions, this discovery could allow fully biocompatible SABRE hyperpolarization processes in water with catalyst recycling. This would allow the production of pure aqueous contrast agents requiring only parahydrogen as a consumable.

Licensing Contact

Chris Harris

615.343.4433

Inventors

Eduard Chekmenev, Boyd Goodson, Fan Shi, Aaron Coffey
Category:
Medical Imaging

Two Degrees-of-Freedom, Fluid Power Stepper Actuator Model

Vanderbilt researchers have developed a novel technology for use of a flexible fluidic actuator in MRI-guided surgical systems. This method eliminates the need for moving the patient out of the MRI machine, onto an operating table, and back in order to perform procedures. It is a safe, sterilized, and successful method to simplify MRI-guided surgical procedures.

Licensing Contact

Taylor Jordan

615.936.7505

Inventors

David Comber, Eric Barth, Jonathan Slightam, Vito Gervasi
Category:
Medical Devices Medical Imaging

Inexpensive Disposable Hydro-Jet Capsule Robot for Gastric Cancer Screening in Low-Income Countries

Gastric cancer is the second leading cause of cancer death worldwide. While screening programs have had a tremendous impact on reducing mortality, the majority of cases occur in low and middle-income countries (LMIC). Typically, screening for gastric and esophageal cancer is performed using a flexible endoscope; however, endoscopy resources for these settings are traditionally limited. With the development of an inexpensive, disposable system by Vanderbilt researchers, gastroscopy and colonoscopy can be facilitated in areas hampered by a lack of access to the appropriate means.

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Pietro Valdastri, Keith Obstein, Christopher Lyne, Robert Caprara, Will Jones, Alexander Vartanian, Douglas Morgan, Erdem Erdemir, Federico Campisano, Christian Di Natali, Gabriel Scozzarro, Marco Beccani
Category:
Medical Devices Medical Imaging Robotics
Field of Use:
Gastrointestinal

Non-Invasive Bacterial Identification for Acute Otitis Media using Raman Spectroscopy

Vanderbilt researchers have developed an optical-based method for real-time characterization of middle ear fluid in order to diagnose acute otitis media, also knows as a middle ear infection. The present technique allows for quick detection and identification of bacteria and can also be applied to other biological fluids in vivo.

Licensing Contact

Masood Machingal

615.343.3548

Inventors

Anita Mahadevan-Jansen, Oscar Ayala, Eric Skaar, Catherine Wakeman, Jay Werkhaven
Category:
Diagnostics Medical Devices Medical Imaging

Self-Decoupled RF Coils for Optimized Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is one of the most important and versatile tools in the repertoire of diagnostics and medical imaging. Vanderbilt researchers have developed a novel, geometry independent, self-decoupling radiofrequency (RF) coil design that will allow MRI machines to generate images at a faster rate and with greater image quality.

Licensing Contact

Brennen Carr

615.343.2430

Inventors

Xinqiang Yan, John Gore, William Grissom
Category:
Medical Devices Medical Imaging

Selective Size Imaging using Filters via Diffusion Times (SSIFT)

Vanderbilt researchers have developed a novel MRI-based method for fast, robust, and accurate imaging of biological tissue by selecting a specific cell size range (such as tumors) without the need for a contrast agent. One exciting application of this method is imaging brain metastases (BM) that are difficult to differentiate from other brain abnormalities such as radionecrosis when using existing approaches.

Licensing Contact

Chris Harris

615.343.4433

Inventors

Junzhong Xu
Category:
Medical Imaging