obesity

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Vanderbilt-developed obesity treatments will be advanced through collaboration with Soleno Therapeutics

Vanderbilt-developed obesity treatments will be advanced through collaboration with Soleno Therapeutics

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Research Press release Alan Bentley Basic Sciences Biochemistry Craig Lindsley Jerod Denton obesity Pharmacology Prader-Willi Syndrome Warren Center for Neuroscience Drug Discovery

Bile acids mediate metabolic benefits of weight-loss surgery

A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery.

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bariatric surgery bile acid Department of Medicine department of surgery diabetes gastroenterology microbiome Mouse Metabolic Phenotyping Center Naji Abumrad obesity Robb Flynn section of surgical sciences Vanderbilt Weight Loss Center weight loss surgery

Enzyme protects against obesity-related heart disease

Saturated fats found in high-fat diets increase the risk of heart failure. Now Manisha Gupte, PhD, Hind Lal, PhD, and colleagues show that the presence of an enzyme called GSK-3beta in the heart is crucial to protect against obesity-related cardiac dysfunction.

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Heart Disease obesity

Pharma Pipeline: Compounds, Core Capabilities, Collaboration

Right now, at Vanderbilt University there are dozens of researchers studying small and large molecules and their effects on various diseases, searching for clues that will lead to the next big drug discovery.

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technology pipelines pharmaceutical Research brain disorders obesity cardiovascular disease   infectious disease HIV malaria cancer