cancer

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Breast cancer-killing RIG

Immune checkpoint inhibitors — cancer therapies that remove the “brakes” on the adaptive anti-tumor immune response — have had remarkable success in melanoma and lung cancer.


Analyzing single-cell landscapes

Single-cell RNA sequencing is a powerful tool for studying cellular diversity, for example in cancer where varied tumor cell types determine diagnosis, prognosis and response to therapy.


Studying cellular deliveries

Many cells, including cancer cells, are known to secrete short RNAs in tiny vesicles, which then move inside other cells — potentially a form of cell-to-cell communication.


Evading cell death

Cancer cells can develop resistance to the treatments designed to eliminate them. Several studies have linked stress granules (SGs), cell organelles that form transiently in response to extracellular stress, to this phenomenon. However, how SGs protect cancer cells remains unclear.