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Pain relievers a risk for C. diff?

Clostridium difficile infection (CDI) is a leading hospital-acquired infection and a major cause of antibiotic-associated diarrhea.

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Health and Medicine Research anti-inflammatories C diff Clostridium difficile Crohn’s and Colitis Foundation of America David Aronoff Department of Medicine diarrhea division of infectious diseases hospital acquired infections hospital-acquired diarrhea mBio NCATS NIAID NIDDK NIH nsaid pathology microbiology and immunology

Unleashing TIGER on small RNAs

Efforts to explore the landscape of small RNAs (sRNAs) — short RNA molecules that are poorly understood — often use high-throughput sequencing (sRNA-seq). These efforts are hampered by a lack of tools to identify, quantify and analyze all the different sRNAs in sRNA-seq datasets.

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American Heart Association Basic Sciences Department of Medicine Journal of Extracellular Vesicles Kasey Vickers Molecular Physiology & Biophysics NCATS NCI NHLBI NIDDK NIGMS NIH RNA

A “public” target for HIV

Individuals produce unique sets of antibodies in response to HIV infection. That diversity — and the ability of the human immunodeficiency virus to rapidly change its protein coat to avoid detection — has stymied efforts to develop an anti-HIV vaccine.

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Health and Medicine Gates Foundation HIV HIV/AIDS Ivelin Georgiev NCATS NHLBI NIAID NIGMS NIH pathology microbiology and immunology Vaccine Vanderbilt Vaccine Center