Infection with the stomach-dwelling bacterium Helicobacter pylori— particularly strains producing the oncoprotein CagA — is a strong risk factor for gastric cancer.
Efforts to explore the landscape of small RNAs (sRNAs) — short RNA molecules that are poorly understood — often use high-throughput sequencing (sRNA-seq). These efforts are hampered by a lack of tools to identify, quantify and analyze all the different sRNAs in sRNA-seq datasets.